Using weapon of mass destruction (WMD) and toxic industrial material (TIM) as a tool for crime and act of terror led to the creation of special Scientific Working Group on the Forensic Collect and Analysis of Chemical, Biological, Radiological, and Nuclear (CBRN) evidence. Investigating authorities must be well prepared to ensure that an investigation was properly investigated and offender responsible for committing this crime suffer for their actions, in accordance with the law. The main purpose of this article is to present methods collecting forensic evidence contaminated with CBRN agents.